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The study included patients who underwent implantation of drug-eluting stents of both the first and second generation. All patients who underwent implantation of the stent without complications (in the first 10 days) were offered a repeated phased clinical examination. Of this observation group, in 62 patients with repeated coronary angiography (CAG), restenosis within the stent was detected more than 50% of the proper lumen of the vessel. The observation period for patients ranged from 3 months. up to 4 years (median follow-up = 2.53 ± 1.29 years). The number of patients for whom PCI was performed ≤ 1 year ago (on average 0.93 ± 0.22) was 22 (35.5%) patients - A-subgroup. The number of people who had PCI performed> 1 year ago (on average 3.30 ± 0.85) was 40 (64.5%) people - the B-subgroup.